Cardizem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Cardizem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, Cardizem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Capsule, Extended Release
• Tablet
• Capsule, Extended Release, 24 HR
• Tablet, Extended Release
• Capsule, Extended Release, 12 HR
• Tablet, Extended Release, 24 HR

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AF patients were then divided into paroxysmal AF, persistent AF, and permanent AF subgroups. Fine needle aspiration cytology of basal cell adenoma of the salivary gland. Recently, hydrodynamic gene delivery using a rapid injection of a relatively large volume of DNA solution has opened up a new avenue for gene therapy studies in vivo. Pelizaeus-Merzbacher disease (PMD) is an X-linked recessive disease caused by coding sequence mutations in the PLP gene, sub-microscopic duplications of variable sizes including the PLP gene or very rarely deletions of the PLP gene.

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Prophylaxis of early thromboses in the surgery of the arteries of the lower extremities CMSARs are feasible with a high procedural success rate resulting in a favorable short-term outcome. Nonsense-mediated mRNA decay in Tetrahymena is EJC independent and requires a protozoa-specific nuclease. To our knowledge, a previous case of axillary soft-tissue mass of ALK-positive ALCL with an alveolar growth pattern has been so far reported in the literature. We show that expression of pal-1 in the postembryonic neuroblast cell V6 can be initiated by two alternate pathways.

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In conclusion, the ADH activity of male rats fell between 30 and 45 d after birth. Malignant teratoma of the ovary with chorioepitheliomatous differentiation These observations suggest that 4 weeks after ligature of the oviduct the destruction of cilia and the increase of secretions may cause an impairment in the ovum transport through the oviduct. Intraocular pressure control was achieved in all patients postoperatively.

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A low reintervention rate along with high patient satisfaction makes DPEJ an attractive alternative to the more commonly placed jejunostomy feeding tubes. The potential uses of this device in corneal research and therapy are discussed. There was no correlation between tumor size and the degree of the inhibitory effect.

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S-acylation is a ubiquitous mechanism in eukaryotes catalyzed by a family of enzymes called Protein S-Acyl Transferases (PATs). In the present study, optical imaging was found to be useful in revealing functional changes and may reflect conditions of reorganization and/or changes in surviving neurons after SCI. We show that, in ES cells, melPRC1 can functionally substitute for other PRC1-like complexes in Hox gene repression.

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In addition to the drugs officially approved for migraine prevention by international governmental regulatory agencies, numerous different agents are commonly used for this indication, showing various levels of evidence of efficacy and tolerability. Three thermal transport regimes - bulk-like, Casimir, and confinement - are emphasized to describe different governing mechanisms at corresponding length scales.

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Synergistic enhancement of in vitro antimicrobial activity of cefmetazole and cefazolin, cefotiam, cefamandole or cefoperazone in combination against methicillin-sensitive and -resistant Staphylococcus aureus. To evaluate the efficacy of a novel tumor receptor-specific small-peptide-near-infrared dye conjugate for tumor detection by optical imaging. Knockdown of PTBP1 decreased the expression of cortactin isoform-a by exclusion of exon 11. Aperture fixation and a rounded tibial bone tunnel exit seem to be a reasonable alternative in PCL reconstruction.

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Comparative study of agograms and rheograms of medullated nerve conduction and of the electronic alterations of these curves Mutations and mechanisms in congenital and age-related cataracts. In general, the activities of lactate dehydrogenase, pyruvate dehydrogenase and succinate dehydrogenase increased in liver, kidney, intestine, ovary, gills and muscles of fish exposed to cadmium for 15 and 30 days. This, in turn, causes local changes in the NW emission quantum yield (QY). National statistics derived from case register data, especially for neurosis and affective disorder, may be unreliable.

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This is probably due to a more pronounced expansion in the anterior area and more accentuated pressure of the upper lip in GrE. The human proteome is rich with protein kinases, and this richness has made the kinase of crucial importance in initiating and maintaining cell behavior. B-type natriuretic peptide in patients with systemic right ventricle. Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin. Neuronal nicotinic acetylcholine receptors: from the gene to the disease.

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Sampling was performed from the anterior, middle, and posterior parts of the CS, inferior petrosal sinus (IPS), and the peripheral vein. In captopril group number of active lever pressing was significantly lower than morphine group however, there was not significant difference between active and passive lever pressed number. Among these stroke models, gerbil models of brain ischemia have been widely used because of several advantages such as easy operability and convenience.

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Both inhibition of ROS generation by tocopherol and inhibition of cytochrome C release by cyclosporine A led to reduction of stretch-induced apoptosis. Finally, Hedgehog potential as a pharmacological target to treat fat mass disorders is discussed. Germline mutations in the tumor suppressor gene, BRCA1, predispose individuals to breast and ovarian cancers. Since their categorization as possible carcinogens, welding fumes have gained increasing attention as high priority agents for risk assessment. Effectiveness of core muscle strengthening for improving pain and dynamic balance among female patients with patellofemoral pain syndrome.

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During experiment in vitro and in the clinical environment in patients with the mandibula fracture there were studied up antimicrobic action of the ozonized distilled water, the ozone concentration in which had constituted 0.3 mg/l. Twenty-five parent-child dyads (with children aged 6-59 months) were video-taped during a 15-min unstructured play situation.

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The cloned protein showed high homology with enzymes belonging to the bacterial subclass of type B carboxylesterases. The molecular modelling suggested that Acasp, from a canine-specific hookworm, would have a higher substrate affinity for canine haemoglobin than for human haemoglobin. Of these, 23 patients belonged to traumatological-and-orthopaedical cohort, 3 to general surgical cohort, 4 to gynaecological, and 18 to vascular cohort (isolated deep vein thrombosis). Investigations on the epizoic fauna of Gadus morhua (L.), Platichthys flesus (L.) and Oncorhynchus mykiss (Walbaum) from the Kiel Fjord and Kiel Bight were carried out from September 1996 to March 1997. Since the determination of the particle size is influenced by the particle shape, therefore microscopic examination is always suggested, which together with image analysis is suitable for the assesment of the most typical parameters.

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Both LPS and LTA contain lipophilic domains and anionic charges that may be susceptible to reactivity with stannous fluoride, a commonly used ingredient clinically proven for the treatment and prevention of gingivitis. Evidence for a metal-ion involved in transport catalysis by use of metallochromic indicators.

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At final follow-up, a personal examination and a standardized questionnaire evaluation were conducted, including the Oswestry Disability Index (ODI) and functional outcome according to modified MacNab criteria. The input data are a sequence of RF data forming a 2D data input, one column for each pulse emission. This suggests that HGF may have a protective effect against adenovirus-induced pathology.

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The increment was inhibited by verapamil, sodium nitroprusside or hypoxia (N2 aeration). Between January 2014 and October 2014, nine patients underwent aortic ViV procedures in our institution.

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At the end of six months, the patient was completely asymptomatic and there were no visible signs of gingival inflammation and tissue irritation at the site of the space maintainer. If subtotal resection is performed the Billroth II anastomosis is preferred, as it is more radical.

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False-negative results in screening programmes: systematic review of impact and implications. Patients on OAC did not have higher 30-day major adverse events than those who were not anticoagulated at index procedure. We also compared the annual number of individuals with HD registered in the database of the National Board of Health and Welfare in these regions, with all of Sweden. Stents matching directly measured ureteral lengths are associated with high rates of ideal stent position. After incubation, the authors examined the plates for the presence of bacterial colonies.

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The real part of the fundamental mode is in fact capable of exceeding the index of refraction of all the materials used while maintaining a manageable imaginary part, as a result of appropriate choice of materials for the dielectric wire and the metal. Multicenter Prospective Clinical Series Evaluating Radiofrequency Ablation in the Treatment of Painful Spine Metastases.

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Verrucous-keratotic forms of malignant melanoma occur more commonly in women and favor the extremities, but may occur on any anatomic site. Observations suggested that the fibril intermingling was point-like and present only in places at the cemento-dentinal junction. To understand dynamic postural control of the higher brain, we compared air-righting reflexes in various decerebrate rats.

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Paclitaxel also increased expression levels of acetylated tubulin and end binding protein 1, markers of microtubule stability and growth, respectively. In addition, patients who are intolerant of traditional treatments (e.g., gastrointestinal problems related to anti-inflammatory medications) can be considered for these injections. Low-dose aspirin, but not vitamin C and vitamin E, has small to moderate benefits when used for the prevention of preeclampsia. Pathophysiology of stroke, although multifactorial, supports embolism rather than flow limitation as the primary mechanism.

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Clinical trials are critical to the development of newer and more effective treatments. Both gabapentin and pregabalin are approved for the management of postherpetic neuralgia (PHN), although dosing and pharmacokinetic differences between these medications may affect their use in actual practice. Competitive substrate and inhibitor interactions at the physiologically relevant active site of nitrogenase. We report experimentally and theoretically on the controllable inhibition of spiking regimes in a 1300 nm wavelength vertical-cavity surface-emitting laser. It should be considered as a reliable alternate for tumours that are benign and most often asymptomatic.

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Amifostine proved to be an effective inhibitor of platelet activation induced in vitro by physiologic inducers. Peroxisomal acyl-CoA oxidation, microsomal CYP4A content and laurate omega-hydroxylation were increased in rat hepatocytes by the addition of 100 microM clofibrate or Wy14,643 for two days. While researchers are increasingly re-conceptualizing international migration, far less attention has been devoted to re-thinking short-distance residential mobility and immobility. Regarding neutrophils, the mRNA expression of hDEFAs and LL-37 increased slightly at 2 and 5 h after the contact with DENV-2. A nationwide survey of veterinary laboratories culturing poultry tissue and environmental samples for Salmonella found a large variation in isolation procedures.

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These ventilatory abnormalities indicate that even in the absence of severe symptoms, the control of the ventilatory response is somewhat impaired in many patients with meningomyelocele. Arbuscular mycorrhizal fungi in chronically petroleum-contaminated soils in Mexico and the effects of petroleum hydrocarbons on spore germination. Rheumatoid arthritis is not as common a problem in Taiwan as it is in western countries. Antithrombotic prophylaxis and treatment of patients with hemorrhage and thrombosis requires careful assessment, interpretation of laboratory workup, and attention to coexistent morbidities. Efficient Formation of Site-Specific Protein-DNA Hybrids Using Copper-Free Click Chemistry.

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Comparison of column chromatographic, colorimetric and electrophoretic methods for determination of glycosylated hemoglobin (HbA1). It is useful for the radiologist to make this diagnosis on imaging so that biopsy can be avoided and surgery performed to avoid complications. The seeding of tumor cells is a critical step in the process of metastasis, but whether and how the microenvironment of target organs affects metastatic seeding remain largely unknown.

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Quantitative determination by polyacrylamide gradient electrophoresis In most cell systems studied, polyamines appear to be most concentrated in cytoplasmic structures. This case illustrates a very rare presentation of lung adenocarcinoma and also represents what the authors believe to be the first report of a solitary skull mass originating from a lung primary. In present study, we discuss a newly constructed follicle model in vitro, which was used to simulate the follicular structure of the thyroid and explore the regulatory roles of iodinated TG in the follicular lumen on NIS expression.

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BMP-2 and BMP-7 can induce a transcriptional response when added to cells coexpressing ActR-I and BMPR-II but not to cells expressing either receptor alone. We used multivariate Cox regression to assess time to plasma viral suppression and logistic regression with generalized estimating equations to assess genital viral shedding for each contraceptive method. Pulmonary embolism refers to obstruction of the pulmonary artery or one of its branches by material (usually a thrombus) that originated elsewhere in the body. HLP or ECG improved the survival of HUVECs from ox-LDL-induced viability loss.

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The active immunization of mice against an intracerebral infection of Haemophilus pertussis organisms by intranasal instillation of H. Tomato plants overexpressing CaKR1 enhanced tolerance to salt and oxidative stress. Doxorubicin (DXR) belongs to the most efficient anticancer drugs. Evidence that estrogens directly alter androgen-regulated prostate development.

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The impact of life stress on adult depression and anxiety is dependent on gender and timing of exposure. We also analyze our model when incentive-based vaccination programs are offered. Cholesterol absorption, as assessed by acute cholesterol uptake, was significantly decreased in the small intestine and liver upon DGAT1 deficiency/inhibition. This time interval exceeds the 6-10 days needed for increments in plasma LH concentrations to stabilize after gonadectomy of ferrets of both sexes.

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The density of NA nerve fibers was measured by quantitative image analysis. Between September 1997 and August 1999, 64 patients with acute ischemic stroke were recruited for MR imaging (ie, diffusion-weighted imaging, perfusion-weighted imaging, MR angiography, T2-weighted imaging) after a baseline CT was performed.

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Mathematical description and experimental analysis of intraspecific animal behavior We perform all type of anaesthesia at Institute for Urology and Nephrology of Clinical Centre of Serbia.

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Top-Down Modulation on the Perception and Categorization of Identical Pitch Contours in Speech and Music. This study examined the role of VA in the anticonvulsive properties of GE in a Sprague-Dawley rat model of epilepsy. Recent evidence indicates that adolescent animals are more sensitive than adults to the disruptive effects of acute ethanol exposure on spatial learning. Anatomical, histological, and cytogenetic studies were undertaken on a horned intersex goat kid and three of its normal litter mates. Between January 2010 and December 2013, 420 patients underwent ACL treatment.

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Impaired multisensory processing in schizophrenia: deficits in the visual enhancement of speech comprehension under noisy environmental conditions. Qualitative description of the limitations of RCTs in providing the information needed by medical decision makers, and demonstration of how evidence from additional sources can aid in decision making, using the examples of deciding whether a 60-year-old woman with mildly elevated blood pressure should take daily low-dose aspirin, and whether a hospital network should implement carotid artery surgery for asymptomatic patients. Our patient had complete resolution of symptoms after treatment with metronidazole. We applied a newly developed bioinformatics system called VirusScan to investigate the viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types and identified 505 virus positive samples with distinctive, organ system- and cancer type-specific distributions.

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Mental health care utilization in prepaid and fee-for-service plans among depressed patients in the Medical Outcomes Study. Reports of increased numbers of IgE-containing plasma cells in rectal biopsy specimens from patients with ulcerative colitis and non-specific proctitis have not been confirmed by others.

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The aqueous extract (AE) showed a significant inhibition of carrageenin-induced rat paw edema at a dose of 400 mg/kg administered orally, but did not block the edema induced by arachidonic acid. The indications, types of skin grafts, and the methods of harvesting grafts are described.

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Up to 600g of water per g of biopolymer may be retained in the electrostatic gel network compared to a protein gel (3-9g of water per g of protein). Dyspepsia and Helicobacter pylori infection in rural south west Cameroon. Furthermore, the numbers of natural killer (NK) and NKT cells in the spleen increased markedly in response to MDT-1 administration. Intrinsic priors for model selection using an encompassing model with applications to censored failure time data.

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A teaching rotation and a student teaching qualification for senior medical students. Multiple mechanisms might account for this situation at the pre-receptor, receptor and post-receptor levels.