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Aldazide (Spironolactone)

Aldazide is a potassium-sparing diuretic that was approved many years ago. Until recently, it was used primarily to treat edema resulting from liver cirrhosis, primary hyperaldosteronism and nephrotic syndrome. It has been used in combination with potassium-wasting diuretics to prevent hypokalemia. Recent research on this older diuretic has focused on its effect in patients with left-sided congestive heart failure (CHF). As an aldosterone-blocking agent, Aldazide is postulated to work synergistically with angiotensin-converting enzyme (ACE) inhibitors to provide more thorough blockade of the renin-angiotensin-aldosterone (RAA) system.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Aldazide comes as a tablet and suspension (liquid; Carospir) to take by mouth. It usually is taken once or twice a day. Take Aldazide suspension consistently either with food or without food each time. Take Aldazide at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Aldazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the oral suspension well before each use to mix the medication evenly.

Your doctor may start you on a low dose of Aldazide and gradually increase your dose.

Aldazide tablets and suspension release the medication differently in your body and cannot be substituted for one another. Only take the Aldazide product prescribed by your doctor and do not switch to a different Aldazide product unless your doctor says that you should.

Aldazide controls high blood pressure, edema, heart failure, and hyperaldosteronism but does not cure these conditions. It may take about 2 weeks or longer before the full effect of Aldazide occurs. Continue to take Aldazide even if you feel well. Do not stop taking Aldazide without talking to your doctor.

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The following eight markers were employed for the haplotype analysis: IFNA, D9S736, D9S1749, D9S942, D9S1748, D9S1604, D9S171, and D9S126. The purpose of this study was to compare the views of community pharmacists on over-the-counter (OTC) omeprazole and simvastatin. Thus, the purpose of this randomized controlled trial (RCT) was to evaluate the effects of self-compassion training on mood and metabolic outcomes among patients with diabetes. Refugee children used fewer psychiatric healthcare services than Danish-born children. Beyond inflammation: airway epithelial cells are at the interface of innate and adaptive immunity.

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Specific cDNA probes for transforming growth factor beta s (TGF-beta s) 1, 2, and 3 and TGF-beta types I, II, and III receptors were used to study expression of the mRNAs of the different TGF-beta ligand and TGF-beta receptor isoforms in cultured non-small cell lung cancer (NSCLC) cells and small cell lung cancer (SCLC) cells. Measurement of long-ranged steric forces between polyelectrolyte layers physisorbed from 1 M NaCl.

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To estimate the prevalence of and relation between Helicobacter pylori (HP) and thyroid disease in a 56-65-year-old population with cardiovascular risk factors. Here, we evaluated the role of 14-3-3epsilon, a chaperone of phosphorylation and cellular-localization determination, in thermal control establishment, which represents hypothalamic plasticity, in chicks. Effect of cold stratification treatments on germination of drought tolerant shrubs seeds. Laparoscopic alternatives to this assisted approach consist of the hand-assisted method and the more conventional facilitated laparoscopic sigmoid resection. Model cemented THJR specimens were prepared in which the femoral canal was textured using specific cutting tools.

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Two alternative proposals about the mechanism behind structural priming include (a) short-term activation from a memory representation of a priming structure and (b) longer term adaptation within the cognitive mechanisms for creating sentences, as a form of procedural learning. These data suggest the significant potential for enhancing a process involved in the cocktail party effect in normally developing individuals and adds to an emerging literature on the potential to enhance auditory ability after only a brief period of visual deprivation. The Leapfrog Group recommends that payers, providers, and vendors collaborate to develop patient safety solutions. Impact of lipids on progression and regression of atherosclerosis. Adaptation to growth in C8166 cells and conversion from the sCD4-resistant to the sCD4-sensitive phenotype represent the emergence to prominence of viral species in the pre-C8166 stock that have a replication advantage in C8166 coincident with increased sensitivity to sCD4.

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A 35-year-old Japanese male, after living in the United States for nine months, suffered from a combination of headache and fever. Gel shift analysis indicated that the oligonucleotide forms a collinear triplex within the duplex Sp-1 binding site. The term therapeutic endoscopic ultrasound (EUS) refers to direct ultrasound guided placement of pharmaceuticals, devices and biological agents for the purpose of treating a disease or symptoms. The uptake of indomethacin into primary cultured rat hepatocytes and COS-7 cells transfected with cDNA encoding sodium taurocholate co-transporting polypeptide or organic anion transporting polypeptide 1 was examined. Treatments, given twice weekly for 4 weeks, consisted of intraperitoneal injections of either mAb.

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A practical approach to extensive bilateral benign tumours of the nasal cavity and paranasal sinuses. Implantable cardioverter-defibrillator deactivation at the end of life: ethical, clinical and communication issues Cirrhosis progression was associated with a significant enhancement of vascular density and expression of vascular endothelial growth factor-A, angiopoietin-1, angiopoietin-2, and placental growth factor in cirrhotic livers. Cytotoxic effects of topotecan combined with various active G2/M-phase anticancer drugs in human tumor-derived cell lines.

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The sedative and analgesic effects of detomidine-butorphanol and detomidine alone in donkeys. Moreover, it was applied for the characterization of the microarray glycans by using known carbohydrate-binding proteins. Drinking water, water used in food production and for irrigation, water for fish farming, waste water, surface water, and recreational water have been recently recognized as a vector for the transmission of pathogenic Escherichia coli, especially serotype O157:H7.

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A substantial amount of static and kinetic work has focused on the binding of pyruvate or substrate mimic oxamate to the binary complex of lactate dehydrogenase (LDH)-NADH where substantial fluorescence quenching is typically observed. Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila. Plain skull radiographs are often contributive to the diagnosis.

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A possible antioxidative role of hydroquinone peroxidase in H(2)O(2) scavenging within the mitochondria, in cooperation with ascorbate or coupled with mitochondrial NAD(P)H dehydrogenases, is proposed. Moral insanity and psychological disorder: the hybrid roots of psychiatry.

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Exploring the significance of morphological diversity for cerebellar granule cell excitability. In this study, we used a more complex time-varying input to mimic the continuous barrage of synaptic input that neurons are likely to receive in vivo. Fat malabsorption assessed by 14C-triolein breath test in HIV-positive patients in different stages of infection: is it an early event?

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The relative biological effectiveness (RBE) of 15 MeV betatron x-rays and 200 KV x-rays for lethality in mice. In particular, most of pol and tat/vpu, as well as the region encoding intracellular domain of gp41, did not cluster with any of the previously characterized HIV-1 subtypes. Radiographic voiding cystourethrography demonstrated bilateral vesicoureteral reflux and multiple pelvoureteric diverticula ranging in size from 2 to 5 mm.

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The mean difference in onset times between elbow and wrist agonists (22-30 ms) remained unchanged across conditions. Blood samples were drawn sequentially in order to determine plasma free insulin concentration. If phages were added to the secondary mycelium at the beginning of spore formation, the phage genome became integrated in the developing spores in a heat-stable state. Effect of Rebonding on the Bond Strength of Orthodontic Tubes: A Comparison of Light Cure Adhesive and Resin-Modified Glass Ionomer Cement In Vitro. Stimulatory effects of intraventricular administration of kynurenines, amino acids, and convulsants: differences between rats and mice

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The function of NUT is unknown, but here we show that NUT contains nuclear localization and export sequences that promote nuclear-cytoplasmic shuttling via a leptomycin-sensitive pathway. Questionnaires pertaining to postoperative surveillance were mailed to 4467 members of the American Urological Association (AUA). Preparation of uniform microcapsules with levofloxacin tablets 500g to oz silicone oil as continuous phase in a micro-dispersion process. A genomewide screen was performed using microsatellite markers spanning approximately 10-cM intervals throughout the genome. Nano-encapsulant of ascorbic acid-loaded apoferritin-assisted photoelectrochemical sensor for protease detection.

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